Section
1 (Sent to NLM in February and March 2008)
New
Agent-Disease Links 2/23/08
These
are Agent-Disease links for the 112 agents sent to NLM on February 3. The
names of the agents are followed by the ID numbers of the linked diseases. See
tables below for names of diseases.
No
established human carcinogen (occupational): 141, 142, 144, 146, 147, 192, 200, 549;
Other
biological toxins: 415, 431
Irritants:249,
285, 563
Hand-arm vibration:
279
Decompression:284 Mercury,
inorganic compounds: 333, 18 (This is a new agent. Also, "Mercury" was
changed to "Mercury, elemental." Alizarin
complexone: 18 Alizarin:
18 Azo
violet: 18 Hydroxynaphthol
blue: 18 Methyl
purple: 18 Phenol
blue: 18 Fungi:
23, 115, 390 Nickel
II chloride hexahydrate: 23 Nickel
II sulfate hexahydrate: 306, 23, 18 Hydrazine
mononitrate: 306, 310, 18 Xenon:
310, 350 Lithium
deuteride: 306 Manganese
dioxide: 25 Deuterium:
350 Potassium
iodide: 18 Urethane:
326 Diethylene
glycol dibutyl ether: 326 Krypton:
350 Potassium
ferricyanide: 351 1,1-Difluorethane:
326, 350 Quinuclidinyl
benzilate: 310 Lanosol
yellow 4G: 23 Ammonium
bifluoride: 247 Calcium
fluoride: 247 Sodium
phosphate, tribasic: 306 FD&C
blue no. 2: 23
New
Agent-Disease Links 3/16/08
These
are Agent-Disease links for the 120 agents sent to NLM on March 16. The
names of the agents are followed by the ID numbers of the linked diseases. See
tables below for names of diseases.
RARE
EARTH METALS: 552; 235 Selenium
oxychloride: 306; 18 Selenium
dioxide: 306; 18 Dimethylmercury:
310 Aldicarb:
66 Acetophenone:
326 SULFITES:
23 Ethylphosphonofluoridic
acid isopropyl ester: 66 Cyclohexyl
sarin: 66 Mercury
II acetate: 333; 18; Lead
II nitrate: 333; 223 Decahydronaphthalene:
326; 325 Ammonium
phosphate, monobasic: 306 1,1,1,2-Tetrafluoroethane:
326; 350
Diseases
in Haz-Map 2/23/08 Excluding Infectious Diseases
| ID |
Disease
Name |
|
Acute Poison |
| 656 |
Acute
tubular necrosis |
| 306 |
Pneumonitis,
toxic |
| 350 |
Asphyxiation,
simple |
| 155 |
Humidifier
fever |
| 326 |
Solvents,
acute toxic effect |
| 82 |
Hepatitis,
chemical |
| 363 |
Inhalation
fever |
| 310 |
Encephalopathy,
acute toxic |
| 351 |
Asphyxiation,
chemical |
| 159 |
Pontiac
fever |
| 158 |
Mill
fever |
| 226 |
Hemolytic
anemia, acute |
| 157 |
Organic
dust inhalation fever |
| 156 |
Grain
fever |
| 154 |
Polymer
fume fever |
| 318 |
Hydrofluoric
acid, toxic effect |
| 390 |
Hypersensitivity
pneumonitis, acute |
| 415 |
Tick
paralysis |
| 66 |
Organophosphate
& carbamates, acute |
| 160 |
Pentachlorophenol/Dinitrophenol,
acute |
| 431 |
Ciguatera
fish poisoning |
| 165 |
Organochlorine
insecticides, acute |
| 210 |
Methemoglobinemia,
acute |
| 389 |
Fumigants,
acute toxic effect |
| 69 |
Metal
fume fever |
| 550 |
Radiation
sickness, acute |
|
Airway |
| 249 |
Asthma,
irritant-induced |
| 255 |
Byssinosis |
| 551 |
Bronchiolitis
obliterans |
| 23 |
Asthma,
occupational |
| 236 |
Pulmonary
disease, chronic obstructive |
| 420 |
Vocal
cord dysfunction, irritant-associated |
|
Occupational Cancer |
| 192 |
Kidney
cancer |
| 190 |
Bone
cancer |
| 189 |
Laryngeal
cancer |
| 200 |
Colorectal
cancer |
| 140 |
Nasal
sinus cancer |
| 2 |
Lung
cancer |
| 32 |
Skin
cancer |
| 549 |
Thyroid
cancer |
| 548 |
Melanoma |
| 547 |
Liver
cancer |
| 3 |
Mesothelioma,
pleural |
| 136 |
Bladder
cancer |
| 147 |
Esophagus
cancer |
| 167 |
Leukemia |
| 141 |
Nasopharynx
cancer |
| 142 |
Pancreatic
cancer |
| 144 |
Brain
cancer |
| 146 |
Stomach
cancer |
| 4 |
Mesothelioma,
peritoneal |
|
Chronic Poison |
| 25 |
Parkinsonism |
| 21 |
Sinusitis,
chronic |
| 282 |
Acro-osteolysis |
| 655 |
Chronic
renal failure |
| 426 |
Carbon
disulfide, chronic toxic effect |
| 333 |
Neuropathy,
toxic |
| 325 |
Encephalopathy,
chronic solvent |
| 308 |
Cataract,
chemical or radiation induced |
| 9 |
Aplastic
anemia |
| 284 |
Osteonecrosis |
| 281 |
Osteomalacia |
| 279 |
Raynaud,
phenomenon of |
| 247 |
Skeletal
fluorosis |
| 307 |
Infertility,
male |
|
Interstitial |
| 1 |
Asbestosis |
| 26 |
Chronic
beryllium disease |
| 552 |
Pneumoconioses,
other |
| 423 |
Asbestos-related
pleural disease |
| 235 |
Pneumoconioses,
benign |
| 117 |
Coal
workers, pneumoconiosis of |
| 118 |
Silicosis,
simple |
| 256 |
Hard
metal disease |
| 257 |
CWP,
complicated |
| 259 |
Silicosis,
complicated |
| 260 |
Silicosis,
acute |
| 115 |
Hypersensitivity
pneumonitis, chronic |
|
Metals |
| 6 |
Cadmium,
chronic toxic effect |
| 13 |
Mercury,
elemental, chronic toxic effect |
| 17 |
Chromium,
chronic toxic effect |
| 36 |
Arsenic,
chronic toxic effect |
| 223 |
Lead,
subacute toxic effect |
| 239 |
Manganese,
chronic toxic effect |
|
Skin |
| 18 |
Contact
dermatitis, allergic |
| 175 |
Oil
acne |
| 266 |
Contact
urticaria |
| 267 |
Contact
dermatitis, photoallergic |
| 285 |
Contact
dermatitis, photoirritant |
| 563 |
Contact
dermatitis, irritant |
| 215 |
Chloracne |
|
Diseases Sorted by ID Number
| ID |
Disease
Name |
| 1 |
Asbestosis |
| 2 |
Lung
cancer |
| 3 |
Mesothelioma,
pleural |
| 4 |
Mesothelioma,
peritoneal |
| 6 |
Cadmium,
chronic toxic effect |
| 9 |
Aplastic
anemia |
| 13 |
Mercury,
elemental, chronic toxic effect |
| 17 |
Chromium,
chronic toxic effect |
| 18 |
Contact
dermatitis, allergic |
| 21 |
Sinusitis,
chronic |
| 23 |
Asthma,
occupational |
| 25 |
Parkinsonism |
| 26 |
Chronic
beryllium disease |
| 32 |
Skin
cancer |
| 36 |
Arsenic,
chronic toxic effect |
| 66 |
Organophosphate
& carbamates, acute |
| 69 |
Metal
fume fever |
| 82 |
Hepatitis,
chemical |
| 115 |
Hypersensitivity
pneumonitis, chronic |
| 117 |
Coal
workers, pneumoconiosis of |
| 118 |
Silicosis,
simple |
| 136 |
Bladder
cancer |
| 140 |
Nasal
sinus cancer |
| 141 |
Nasopharynx
cancer |
| 142 |
Pancreatic
cancer |
| 144 |
Brain
cancer |
| 146 |
Stomach
cancer |
| 147 |
Esophagus
cancer |
| 154 |
Polymer
fume fever |
| 155 |
Humidifier
fever |
| 156 |
Grain
fever |
| 157 |
Organic
dust inhalation fever |
| 158 |
Mill
fever |
| 159 |
Pontiac
fever |
| 160 |
Pentachlorophenol/Dinitrophenol,
acute |
| 165 |
Organochlorine
insecticides, acute |
| 167 |
Leukemia |
| 175 |
Oil
acne |
| 189 |
Laryngeal
cancer |
| 190 |
Bone
cancer |
| 192 |
Kidney
cancer |
| 200 |
Colorectal
cancer |
| 210 |
Methemoglobinemia,
acute |
| 215 |
Chloracne |
| 223 |
Lead,
subacute toxic effect |
| 226 |
Hemolytic
anemia, acute |
| 235 |
Pneumoconioses,
benign |
| 236 |
Pulmonary
disease, chronic obstructive |
| 239 |
Manganese,
chronic toxic effect |
| 247 |
Skeletal
fluorosis |
| 249 |
Asthma,
irritant-induced |
| 255 |
Byssinosis |
| 256 |
Hard
metal disease |
| 257 |
CWP,
complicated |
| 259 |
Silicosis,
complicated |
| 260 |
Silicosis,
acute |
| 266 |
Contact
urticaria |
| 267 |
Contact
dermatitis, photoallergic |
| 279 |
Raynaud,
phenomenon of |
| 281 |
Osteomalacia |
| 282 |
Acro-osteolysis |
| 284 |
Osteonecrosis |
| 285 |
Contact
dermatitis, photoirritant |
| 306 |
Pneumonitis,
toxic |
| 307 |
Infertility,
male |
| 308 |
Cataract,
chemical or radiation induced |
| 310 |
Encephalopathy,
acute toxic |
| 318 |
Hydrofluoric
acid, toxic effect |
| 325 |
Encephalopathy,
chronic solvent |
| 326 |
Solvents,
acute toxic effect |
| 333 |
Neuropathy,
toxic |
| 350 |
Asphyxiation,
simple |
| 351 |
Asphyxiation,
chemical |
| 363 |
Inhalation
fever |
| 389 |
Fumigants,
acute toxic effect |
| 390 |
Hypersensitivity
pneumonitis, acute |
| 415 |
Tick
paralysis |
| 420 |
Vocal
cord dysfunction, irritant-associated |
| 423 |
Asbestos-related
pleural disease |
| 426 |
Carbon
disulfide, chronic toxic effect |
| 431 |
Ciguatera
fish poisoning |
| 547 |
Liver
cancer |
| 548 |
Melanoma |
| 549 |
Thyroid
cancer |
| 550 |
Radiation
sickness, acute |
| 551 |
Bronchiolitis
obliterans |
| 552 |
Pneumoconioses,
other |
| 563 |
Contact
dermatitis, irritant |
| 655 |
Chronic
renal failure |
| 656 |
Acute
tubular necrosis |
|
Mapping
Rules for Lead Compounds
All
lead compound are linked to 223 (Lead Poisoning) and are also linked to a neurological disease,
either 310 (Acute Toxic Encephalopathy) for organic lead compounds or 333
(Toxic Neuropathy) for other lead compounds. Organic lead compounds are also
linked to 226 (Acute Hemolytic Anemic). All lead compounds are also linked to the
Adverse Effects: Secondary Hepatotoxin, Reproductive Toxin, and Nephrotoxin.
Lead:
223, 226, 307, 333, 655, 656 Lead
chromate: 223, 333 Lead
arsenate: 223, 333 Lead
IV oxide: 223, 333 Lead
II sulfate: 223, 333 Lead
II nitrate: 223, 333 Tetraethyl
lead: 223, 226, 310 (Deleted 307) Tetramethyl
lead: 223, 226, 310 (Deleted 307) Lead
azide: 223, 333 Lead
II thiocyanate: 223, 333 Lead
nitroresorcinate: 223, 333 Lead
styphate: 223, 333 Lead
II acetate trihydrate: 223, 333 Changes
Made in Review of "Health Hazard Summaries
for
Industrial and Occupational Chemicals" [Olson, Table IV-4]
Benzonitrile:
160, delete 351 Bromine
pentafluoride: 247 p-Dichlorobenzene:
310 2-Diethylaminoethanol:
18 Dinitro-o-cresol:
160 Dinitrophenol:
160 4,6-Dinitro-o-sec-butyl
phenol: 160 Dinocap:
160 2.4-Dinitrophenol:160 Diglycidyl
ether: 18, 306 Epichlorohydrin:
306 2-Ethylaminoethanol:
18 Ethylene
dichloride: delete 306 Ethyl
silicate: 326 Furfural:
310 Glycidol:
delete 18 Iodine:
306 Oxalic
acid: 306 Oxygen
difluoride: 247 Mercury,
elemental: delete 18 Petroleum
gas (liquified): 326 Propylene
oxide: 306, 310 Methylamine:
306 Sodium
azide: 306 Styrene:
delete 18 Tellurium
and compounds: 310 Additions
Made in Review of Kidney Diseases
1,4-Dioxane:
656 Arsine:
656 Cadmium
and compounds: 656, 655 Carbon
tetrachloride: 656 Chromium
and compounds: 656 Dinitro-o-cresol:
656 Dinitrophenol:
656 Diquat:
656 Lead:
656, 655 Mercury,
elemental: 655 Paraquat
dichloride: 656 Pentachlorophenol:
656 Stibine:
656 Uranium
and compounds: 656 Review
of 663 Chemicals Added to Haz-Map Sometime in the 1990s
Completed
March 8, 2008 New
Links Added to Group I (First 110 Chemicals) Acrylic
acid: 306 Hexachloroethane:
310 Nitric
oxide: 306 New
Links Added to Group II (Second 110 Chemicals) Boron
trifluoride: 247 Bromine
pentafluoride: 247 n-Butane:
350 tert-Butyl
chromate: 310 Camphor,
synthetic: 310 Caprolactam:
310 Catechol:
310 alpha-Chloroacetophenone:
306 bis-Chloromethyl
ether: 306 Chloromethyl
methyl ether: 306 Chromyl
chloride: 306 Vinyl
bromide: 326 Vinyl
fluoride: 326 Vinylidene
chloride: 326 New
Links Added to Group III (Third 110 Chemicals) 2-Nitropropane:
326 1,3-Dichloro-5,5-dimethylhydantoin:
306 Diethyl
ketone: 325 o-Dichlorobenzene:
325 Ethyl
butyl ketone: 325 Ethylidene
norbornene: 326 Formamide:
326 Isobutyl
acetate: 325 N-Isopropylaniline:
18 p-Toluidine:
18 Vinyl
cyclohexene dioxide: 306 New
Links Added to Group IV (Fourth 110 Chemicals) Dimethylaminopropionitrile:
333 Methyl
acetylene-propadiene mixture: 326; 325 Methylcyclohexanol:
325 Morpholine:
306 Nitroethane:
326 Nitrogen
trifluoride: 247 1-Nitropropane:
326; 325 Nonane:
325 Oxygen
difluoride: 247 Phenylphosphine:
226 Phosphoric
acid: 306 Thioglycolic
acid: 306 New
Links Added to Group V (Fifth 110 Chemicals) N,N-Dimethyl-1,3-propanediamine:
306 Hexachlorophene:
18; 310 p-Nitrochlorobenzene:
18 4-Nitrophenol:
18 Sodium
fluoride: 247 Sulfur
tetrafluoride: 247 Triethylene
tetramine: 306 New
Links Added to Group VI (Last 113 Chemicals) Benzotriazole:
18 Benzylamine:
306 Bithionol:
18; 267 Boron
trifluoride etherate: Delete 326 1-Bromo-2-propanol:
326 Butylated
hydroxyanisole: 23 Chloramide:
Delete 23 Dichlorophen:
18 Ethyl
lactate: 326; 325 Ethyl-3-ethoxypropionate:
326 Fentichlor:
267 Tetramethyl
ammonium hydroxide: 306 Triclosan:
18; 267 Change
of Links to Chronic Solvent Encephalopathy (ID 325)
Instead
of the previous rule of linking to all agents tagged with the adverse effect
"Solvent Syndrome," this disease is now linked with all chemicals
that are so tagged AND they are also linked to the Process "Painting
(Solvents)." Any other chemicals, such as Styrene, with strong
epidemiologic evidence of association with chronic solvent syndrome will also
be linked to this disease. The following table shows all chemicals linked to
Acute Solvent Syndrome. Chemicals that are also linked to Chronic Solvent
Encephalopathy are shown in bold.
|
1,1,1,2-Tetrachloro-2,2-difluoroethane
1,1,1,2-Tetrachloroethane
1,1,1,2-Tetrafluoroethane
1,1,1-Trichloroethane
1,1,2,2-Tetrabromoethane
1,1,2,2-Tetrachloro-1,2-difluoroethane
1,1,2,2-Tetrachloroethane
1,1,2-Trichloro-1,2,2-trifluoroethane
1,1,2-Trichloroethane
1,1-Dichloroethane
1,1-Difluoroethane
1,2,3,4-Tetrahydronaphthalene
1,2,3-Trichloropropane
1,2,4,5-Tetrachlorobenzene
1,2,4-Trichlorobenzene
1,2-Dichloroethylene,
all isomers
1,3-Dichloropropene
1,3-Dioxolane
1,4-Dioxane
1-Bromo-2-propanol
1-Bromopropane
1-Hexanol
1-Hexene
1-Nitropropane
2,2-Dimethylbutane
2-Butanone
2-Butoxyethanol
2-Butoxyethyl
acetate
2-Ethoxyethanol
2-Ethoxyethyl
acetate
2-Isopropoxyethanol
2-Methoxyethanol
2-Nitropropane
4-Vinyl
cyclohexene
Acetone
Acetophenone
Acetyl
acetone
Acetylene
alpha-Methyl
styrene
Benzene
Benzyl
acetate
Bromobenzene
Bromoform
Butyrolactone
Carbon
tetrabromide
Carbon
tetrachloride
CHLORINATED
SOLVENTS
Chlorobenzene
Chlorobromomethane
Chlorodifluoromethane
CHLOROFLUOROCARBONS
Chloroform
Chloropentafluoroethane
Chloropropanol
Chlorotrifluoromethane
Collodion
Cumene
Cycloheptane
Cyclohexane
Cyclohexanol
Cyclohexanone
| |