ANTU

Agent Name
ANTU
Alternative Name
alpha-Naphthyl thiourea
CAS Number
86-88-4
Formula
C11-H10-N2-S
Major Category
Pesticides
Synonyms
alpha-Naphthyl thiocarbamide; 1-Naphthyl thiourea; alpha-Naphthyl thiourea
Category
Rodenticides
Description
White crystalline or gray, odorless powder. [rodenticide]
Comments
The lethal oral dose in humans is about 4 g/kg; TLV based on thyroid effects and nausea; In high-dose feeding and intraperitoneal injection studies, animals develop liver injury, pleural and pericardial effusions, and pulmonary edema. [ACGIH]
Restricted
No ANTU products are registered in the USA. [LaDou, 4th Ed., p. 564]
Reference Link #1
NIOSH Occupational Health Guidelines for Chemical Hazards: ANTU
Biomedical References
Search PubMed

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.3 mg/m3
PEL (OSHA)
0.3 mg/m3
IDLH (NIOSH)
100 mg/m3
Excerpts from Documentation for IDLHs
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ANTU. However, based on acute oral toxicity data in humans [Stolman 1969] and animals [Gosselin et al. 1984; Perkow 1971/76], the original IDLH for ANTU (100 mg/m3) is not being revised at this time.

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Not Classifiable

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: