Benomyl

Agent Name
Benomyl
CAS Number
17804-35-2
Formula
C14-H18-N4-O3
Major Category
Pesticides
Benomyl formula graphical representation
Synonyms
1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat [German]; 1-(Butylcarbamoyl)-2-benzimidazolecarbamic acid, methyl estter; 1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol [German]; Agrocit; Arbortrine; Arilate; BBC; BC 6597; BNM; Benlate; Benlate 50; Benlate 50 W; Benomyl; Benomyl 50W; Benomyl-Imex; Chinoin-fundazol; D 1991; Du Pont 1991; Dupont 1991; F 1991; F1991; Fundazol; Fungicide D-1991; Fungochrom; Kribenomyl; MBC; Methyl 1-(butylamino)carbonyl-1H-benzimidazol-2-ylcarbamate; Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate; Methyl 1-(butylcarbamoyl)-2-benzimidazolylcarbamate; Methyl N-(1-butylcarbamoyl-2-benzimidazole)carbamate; NS 02; NS 02 (fungicide); Tersan 1991; Uzgen; [ChemIDplus]
Category
Fungicides
Description
White crystalline solid with a faint, acrid odor. [fungicide] [Note: Decomposes without melting above 572 degrees F.]; [NIOSH]
Sources/Uses
A systemic fungicide with inhibitory effects on mites used on apples, soybeans, celery, beans, sugarcane, peanuts, nuts, citrus, grapes, mushrooms, berries, tomatoes, mangoes, avocados, vegetable crop seeds, rice, bulbs, grasses, shade trees, and other crops; In addition to a fungicide, has also been used in the manufacturing of textiles and paint pigments, as an oxidizing agent in sewage treatment, and as a drug (veterinarian anthelmintic); [ACGIH]
Comments
It is classified as "practically nontoxic"; [EXTOXNET] Allergic contact dermatitis in agricultural workers; [Marks] In high-dose reproductive studies of animals, benomyl causes testicular damage, fetal losses, and birth defects. [Frazier, p. 234-6] "Substances that have been shown to induce genetic damage in germ cells of humans or animals, or which produce mutagenic effects in somatic cells and have been shown to reach the germ cells in their active forms." [MAK] A dermal sensitizer; TLV Basis: Upper respiratory tract irritation; male reproductive system, testicular, and embryo/fetal damage; [ACGIH] A weak skin sensitizer; [Kanerva, p. 1754]
Reference Link #1
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
1 mg/m3, inhalable particulate matter
PEL (OSHA)
15 mg/m3(total dust), 5 mg/m3(respirable fraction)
Vapor Pressure
3.7E-09 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2

Adverse Effects

Skin Sensitizer
Yes
Reproductive Toxin
Yes
ACGIH Carcinogen
Confirmed Animal

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: