3-Chloro-p-toluidine

Synonyms

1-Amino-3-chloro-4-methylbenzene; 2-Chloro-4-aminotoluene; 3-Chloro-4-methylaniline; 3-Chloro-4-methylbenzenamine; 3-Chloro-4-methylphenylamine; 4-Amino-2-chlorotoluene; 4-Methyl-3-chloroaniline; DRC 1339; DRC 1347; Benzenamine, 3-chloro-4-methyl-; p-Toluidine, 3-chloro-; [ChemIDplus] UN2239

Category

Amines, Aromatic

Description

Brown solid; [CAMEO] Low melting solid; mp = 22-25 deg C; [MSDSonline]

Sources/Uses

Used as a bird control agent and in the production of the acid dye palatine fast yellow; [HSDB]

Comments

A mutagen; Causes weakness and cyanosis in lethal-dose studies of rats; [RTECS] Negative evidence of carcinogenicity in studies of rats and mice; [NTP] Emergency treatment: methemoglobinemia; Toluidine compounds (both o- and p-) may cause methemoglobinemia and hemorrhagic cystitis, but the chlorinated derivatives are more potent in producing these effects; [HSDB] Skin sensitizer from human and guinea pig testing; [EPA Hazard Characterization: Chloroanilines Cluster - 2008] An irritant; Effects in high-dose animal studies include cyanosis; [MSDSonline]

Biomedical References

0.041 mm Hg

Explanatory Notes

Flash point = 136 deg C; [eChemPortal: IUCLID] The Guide in the Emergency Response Guidebook is for "Chlorotoluidines, solid." VP from ChemIDplus;

Yes

MetHgb is secondary toxic effect

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)