4,4'-Dithiodimorpholine

Agent Name
4,4'-Dithiodimorpholine
CAS Number
103-34-4
Formula
C8-H16-N2-O2-S2
Major Category
Nitrogen Compounds
4,4'-Dithiodimorpholine formula graphical representation
Synonyms
4,4'-Dithiobis(morpholine); 4,4'-Dithiomorpholine; Accel R; Bismorpholino disulfide; Deovulc M; Dimorpholine N,N'-disulfide; Dimorpholine disulfide; Dimorpholino disulfide; Disulfide, dimorpholino-; Dithiobismorpholine; Morpholine disulfide; Morpholine, 4,4'-dithiobis-; Morpholine, 4,4'-dithiodi-; Morpholine, N,N'-disulfide-; Morpholino disulfide; Morpholinodisulfide; N,N'-Bismorpholine disulfide; N,N'-Dithiodimorfolin [Czech]; N,N-Dithiodimorpholine; Sanfel R; Sulfasan; Sulfasan R; Vanax A; Vulnoc; [ChemIDplus] DTDM; [EPA]
Category
Morpholines
Description
Gray to tan solid; [Hawley] White solid; [MSDSonline]
Sources/Uses
Used as a stain protector for rubber, a vulcanizer (sulfur donor) and accelerator for natural and synthetic rubbers, a fungicide, and a curing agent for poly(fluoroalkoxyphosphazenes); [HSDB]
Comments
Effects in high-dose feeding studies of rats include anemia and liver changes; Emergency treatment: "Morpholine"; Morpholine is an irritant that can cause corneal damage; Liver and kidney injury occur in lethal-dose studies of laboratory animals; [HSDB] Causes abnormal liver function tests in feeding studies of rats; [RTECS] Not irritating to skin but irritating to eyes in rabbits; Not sensitizing; Decrease in fetal viability and body weight, and minor increase in malformed fetuses at materno-toxic doses; Not mutagenic; [EPA Hazard Characterization Document] Irritating but not sensitizing in patch test with ten volunteers; [EPA HPVIS] May cause irritation; [Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
3.05E-05 mm Hg
Lethal Concentration
LC50 (mice) = 1,624 mg/m3/4h
Explanatory Notes
Flash point = 121 deg C; [HSDB]

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: