Bromadiolone

Synonyms

(Hydroxy-4 coumarinyl 3)-3 phenyl-3 (bromo-4 biphenylyl-4)-1 propanol-1 [French]; (Hydroxy-4-coumarinyl-3)-3-phenyl-3-(bromo-4-biphenylyl-4)-1-propanol-1 [French]; 2H-1-Benzopyran-2-one, 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxy-; 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)3-hydroxy-1-phenylpropyl)-4-hydroxy-2H-1-benzopyran-2-one; 3-(3-(4'-Bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxycoumarin; 3-(4-Hydroxy-2-oxochromen-3-yl)-3-phenyl-1-(4-bromobiphenyl)propan-1-ol; 3-(4-Hydroxycoumarin-3-yl)-3-phenyl-1-(4-bromobiphenyl)propan-1-ol; 3-(alpha-(p-(p-Bromophenyl)-beta-hydroxyphenethyl)benzyl)-4-hydroxycoumarin; 3-(alpha-(p-Bromophenyl)-beta-hydroxyphenethyl)benzyl-4-hydroxycoumarin; Boldo; Boot hill; Bromatrol; Bromone; Bromore; Broprodifacoum [South Africa]; Canadien 2000; Contrac; Contrax; Coumarin, 3-(alpha-(p-(p-bromophenyl)-beta-hydroxyphenethyl)benzyl)-4-hydroxy-; Eradic; LM-637; Maki; Rafix; Ratimus; Rotox; Sup'operats; Super-Cald; Super-caid; Super-rozol; Temus; Topidion; [ChemIDplus] UN3027

Category

Rodenticides, Anticoagulant

Description

White to off-white solid; [Merck Index] Technical product is yellowish solid; [HSDB] Yellowish-white odorless solid; [Reference #2]

Sources/Uses

Used as second generation anticoagulant rodenticide; Developed for commensal rodents (even those with resistance to first generation anticoagulants) and voles; [HSBD]

Comments

A vitamin K antagonist; The only significant adverse effect observed in 90 day oral rat studies was reduction in prothrombin time; No evidence of developmental toxicity or teratogenicity in rats and rabbits; [HSDB] Biphasic liver elimination which is initially rapid at 2-8 days followed by a slow phase with a 170 day half life; Not irritating to skin and mildly irritating to eyes; No evidence of teratogenicity or mutagenicity; [INCHEM PDS: Bromadiolone - 1996] No information on reproductive or lactation effects; [REPROTOX] See "Warfarin."

Applied in and around buildings, in transport vehicles, and in sewers; [Reference #1]

Reference Link #1

Biomedical References

1.5E-08 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Coumarin derivative pesticide, solid, poisonous."

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)