Sulfaquinoxaline

Synonyms

2-(p-Sulfanilamido)quinoxaline; 2-Sulfanilamidobenzopyrazine; 2-Sulfanilamidoquinoxaline; 2-p-Aminobenzenesulfonamidoquinoxaline; 2-p-Aminobenzenesulphonamidoquinoxaline; 4-Amino-N-2-quinoxalinylbenzenesulfonamide; Anti-K; Avicocid; Compound 3-120; Italquina; Kokozigal; N(sup 1)-(2-Quinoxalinyl)sulfanilamide; N-(2-Quinoxalinyl)sulfanilamide; SQ 40; SQX; Sulfa-Q 20; Sulfabenzpyrazine; Sulfacox; Sulfaline; Sulfaquinoxalina [INN-Spanish]; Sulfaquinoxalinum [INN-Latin]; Sulphaquinoxaline; Sulquin; Ursokoxaline; [ChemIDplus]

Category

Other Aromatics (Nitrogen)

Description

Solid; [Merck Index]

Sources/Uses

Used for treatment of coccidiosis and other bacterial and protozoal infections in animals; Used formerly in the US in combination with warfarin for controlling rats and mice (kills vitamin K-producing bacteria in the digestive tract); [HSDB]

Comments

A flock of chickens treated with 0.05% in feed for 2-3 days, removed 2 days, and treated again for 2-3 days had 47% mortality with hemorrhages, bone marrow pallor, and septicemia; Emergency treatment: "Sulfonamides"; Sulfonamides are used as antibiotics; They can cause hypersensitivity reactions including erythema multiforme and liver injury; Methemoglobinemia and renal failure may occur after toxic ingestions; [HSDB] Causes changes in renal tubules in 26-week, intermittent, oral study of rats (9100 mg/kg); Causes hemorrhage in 14 day intermittent study of dogs (1400 mg/kg); [RTECS] May cause irritation; May cause skin and respiratory sensitization; [Aldrich MSDS]

Not registered for use in the US; [HSDB]

Biomedical References

3E-10 mm Hg

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)