Cyclohexene

Synonyms

1,2,3,4-Tetrahydrobenzene; 3,4,5,6-Tetrahydrobenzene; Benzene tetrahydride; Benzene, tetrahydro-; Benzenetetrahydride; Cyclohex-1-ene; Cykloheksen [Polish]; Hexanaphthylene; Tetrahydrobenzene; [ChemIDplus] UN2256

Category

Aliphatics, Unsaturated

Description

Colorless liquid with a sweet odor; [NIOSH]

Sources/Uses

Used in organic synthesis and as a solvent for oil extraction and catalysts; [ACGIH]

Comments

TLV Basis = Liver effects; No human studies available; [ACGIH] Exposed laboratory animals show loss of righting reflex and staggering gait. [HSDB] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC]

Biomedical References

No

20 ppm

300 ppm

2000 ppm

Excerpts from Documentation for IDLHs

Other animal data: A chronic inhalation study (6 hours/day, 5 days/week for 6 months) in rats, guinea pigs, and rabbits at concentrations of 150, 300, and 600 ppm showed that although significant increases in alkaline phosphatase occurred in all three groups, most of the hematologic parameters measured were within normal limits [Laham 1976].

89 mm Hg

0.18 ppm

LC (rat) = > 6,370 ppm/4H

Explanatory Notes

Odor threshold from AIHA; Flash point = 11 deg F; VP from HSDB;

may ignite at ambient temp

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Petroleum Production and Refining