Agent Name
CAS Number
Major Category
Metam-sodium formula graphical representation
A7 Vapam; BAY 5590; Basamid-fluid; Carbam; Carbamic acid, N-methyldithio-, sodium salt; Carbamic acid, methyldithio-, monosodium salt; Carbamodithioic acid, methyl-, monosodium salt; Carbathion; Carbathione; Carbation; Carbothion; Diethylamino-2,6-acetoxylidide; Geort; Karbation; Mapasol; Masposol; Metam sodium; Metam-Sodium [ISO]; Metam-fluid BASF; Metamsodium; Metham [German]; Metham sodium; Metham sodium (VAN); Methan-sodium; Methylcarbamodithioic acid sodium salt; Methyldithiocarbamic acid, sodium salt; Methyldithiokarbaman sodny [Czech]; Monam; Monosodium methylcarbamodithioate; N-869; N-Methylaminodithioformic acid sodium salt; N-Methylaminomethanethionothiolic acid sodium salt; N-Methyldithiocarbamate de sodium [French]; N-Metil-ditiocarbammato di sodio [Italian]; Natrium-N-methyl-dithiocarbamaat [Dutch]; Natrium-N-methyl-dithiocarbamat [German]; Nematin; SMDC; Sectagon II; Sepivam; Sistan; Sodium N-methylaminodithioformate; Sodium N-methylaminomethanethionothiolate; Sodium N-methyldithiocarbamate; Sodium metam; Sodium metham; Sodium methylcarbamodithioate; Sodium methyldithiocarbamate; Sodium monomethyldithiocarbamate; Soil-Prep; Solasan 500; Solesan 500; Sometam; Trapex; Trimaton; VDM; VPM; VPM (fungicide); Vapam; Metam sodium solution; Sodium N-methyldithiocarbamate solution; [ChemIDplus]
Dithiocarbamates (Pesticide)
White crystals; [HSDB] Aqueous solution: Yellow to light yellow-green liquid with an odor of amine and sulfur; [CAMEO] White solid with an odor of sweet onions; [EFSA] White crystals; [Aldrich MSDS]
Used as a fungicide and nematicide; [Kanerva, p. 1834] Used as a soil fumigant for control of weeds, weed seeds, nematodes, fungi, and soil insects; [Merck Index] Used as non-selective soil fumigant that possesses fungicidal, herbicidal, insecticidal, and nematicidal properties; Approved for use on food, feed, and fiber crops, turf grass, sewers, and drained ponds and lakes (California only); Also used as antimicrobial agent for wood poles, leather processing, sugar cane and beet processing, sewage sludge, and animal waste; [Reference #2] Approved for use in the EU as a pre-plant soil disinfectant for vegetables, fruit trees, grape vines, nurseries, ornamentals, and other crops; [EFSA]
Allergic contact dermatitis reported in farmworkers; [Kanerva, p. 1834] Slowly reacts with water forming flammable and toxic decomposition products (carbon disulfide, monomethylamine, methylisothiocyanate, and hydrogen sulfide); A skin, eye, and respiratory tract irritant; [CAMEO] A skin, eye, and mucous membrane irritant; May cause skin sensitization; Formation of methylisothiocyanate in water or from skin moisture may also illicit an allergic response; May be fatal by skin absorption; Emergency treatment: "Carbamate herbicides and fungicides"; [HSDB] Rapidly degraded in the environment forming methyl isothiocyanate (MITC), which is the primary volatile active fumigant; Metabolites include MITC and carbon disulfide; [Reference #2] Causes zonal hepatitis in oral studies of rats and mice; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; May cause skin sensitization; Toxic by ingestion and skin absorption; [Aldrich MSDS] See "Methyl isothiocyanate."
Restricted use pesticide for application on golf courses, small areas of turf and soil, and in sewers and drains; [Reference #2]
Biomedical References

Exposure Assessment

Vapor Pressure
4.53E-09 mm Hg
Lethal Concentration
LC50 (rat) = 2,270 mg/m3
Explanatory Notes
Non-volatile; [HSDB]
Reference Link #2

Adverse Effects

Skin Sensitizer
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent


Occupational diseases associated with exposure to this agent: