Ethoxyquin

Synonyms

1,2-Dihydro-2,2,4-trimethyl-6-ethoxyquinoline; 1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline; 2,2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline; 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline; 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline; Alterungsschutzmittel EC; Amea 100; Antage AW; Antioxidant EC; Aries Antox; Dawe's nutrigard; EMQ; EQ; Ethoxychin [Czech]; Ethoxyquin [ISO]; Ethoxyquine; Niflex; Niflex D; Nix-Scald; Nocrac AW; Nocrack AW; Permanax 103; Quinol ED; Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-; Santoflex A; Santoflex AW; Santoquin; Santoquine; Santoquine (VAN); Stop-Scald; [ChemIDplus]

Category

Animal Feed Additives

Description

Yellow liquid; [Merck Index] Light yellow to dark brown viscous liquid with an odor like mercaptans; Darkened by light and air; [CAMEO] Formulated as an emulsifiable concentrate and an impregnated wrap; [Reference #2] Dark brown liquid; [Aldrich MSDS]

Sources/Uses

Used as an additive to animal feed; [Kanerva, p. 1793] Used as an antioxidant for food and feed and as anti-degradation agent for rubber; [Merck Index] Also used as a post-harvest dip for apples and pears; [ChemIDplus] Registered in the US as an antioxidant for the control of post-harvest scald (browning) in pears; Also registered with the FDA as a preservative for animal feed, dehydrated crops, sorghum, and for color preservation in chili powder, paprika, and ground chili; [Reference #2]

Comments

Allergic contact dermatitis reported in a feed mill worker; [Kanerva, p. 1793] A skin irritant; May cause reversible changes to the liver; Reports of contact dermatitis in animal feed employees; [HSDB] May polymerize on exposure to light and air; A skin and eye irritant; May cause skin sensitization; [CAMEO] Strongly associated with cases of occupational contact dermatitis; Causes increased liver enzymes in animal experiments; [Reference #2]

Reference Link #1

Biomedical References

0.000132 mm Hg

Explanatory Notes

VP = 0.000256 mm Hg at 77° F (NTP, 1992); [CAMEO]

Reference Link #2

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Farming (Feed Additives)
• Farming (Pesticides)