Fonofos

Synonyms

(+-)-O-Ethyl S-phenyl ethylphosphonodithioate (8CI)(9CI); Difonate; Difonatul; Doubledown; Dyfonate; Dyfonate Tillam 1-4E; Dyphonate; Ethylphosphonodithioic acid O-ethyl S-phenyl ester; Fonophos; N-2788; N-2790; O-Aethyl-S-phenyl-aethyl-dithiophosphonat [German]; O-Ethyl S-phenyl ethyldithiophosphonate; O-Ethyl S-phenyl ethylphosphonothiolothionate; O-Ethyl-S-phenyl ethylphosphonodithioate; OMS 410; Phosphonodithioic acid, ethyl-, O-ethyl S-phenyl ester; Stauffer N 2790; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Light-yellow liquid with an aromatic odor. [insecticide]; [NIOSH]

Sources/Uses

Used primarily on corn, and also on sugar cane, peanuts, tobacco, turf, and vegetables; [EXTOXNET]

Comments

Classified as "highly toxic," the more concentrated formulations of fonofos may be used only by certified applicators. It persists in soil with a half-life of about 40 days. [EXTOXNET] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Yes

0.1 mg/m3, inhalable fraction and vapor

0.0002 mm Hg

LC50 (rat) = 1,900 mg/m31h

Reference Link #2

Not Classifiable

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)