Atrazine

Agent Name
Atrazine
CAS Number
1912-24-9
Formula
C8-H14-Cl-N5
Major Category
Pesticides
Atrazine formula graphical representation
Synonyms
1,3,5-Triazine-2,4-diamine, 6-chloro-N-ethyl-N'-(1-methylethyl)- (9CI); 1-Chloro-3-ethylamino-5-isopropylamino-2,4,6-triazine; 1-Chloro-3-ethylamino-5-isopropylamino-s-triazine; 2-Aethylamino-4-chlor-6-isopropylamino-1,3,5-triazin [German]; 2-Aethylamino-4-isopropylamino-6-chlor-1,3,5-triazin [German]; 2-Chloro-4-(2-propylamino)-6-ethylamino-s-triazine; 2-Chloro-4-ethylamineisopropylamine-s-triazine; 2-Chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine; 2-Chloro-4-ethylamino-6-isopropylamino-s-triazine; 2-Ethylamino-4-isopropylamino-6-chloro-s-triazine; 6-Chloro-N-ethyl-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine; 6-Chloro-N2-ethyl-N4-isopropyl-1,3,5-triazine-2,4-diamine; A 361; Aatram; Aatram 20G; Aatrex; Aatrex 4L; Aatrex 80W; Aatrex nine-O; Actinite PK; Akticon; Aktikon; Aktikon PK; Aktinit A; Aktinit PK; Aneldazin; Argezin; Atazinax; Atranex; Atrasine; Atrataf; Atratol; Atratol A; Atrazin; Atrazine; Atred; Atrex; Azoprim; Candex; Ceasin 50; Cekuzina-T; Chromozin; Crisatrina; Crisazine; Cyazin; Farmco atrazine; Fenamin; Fenamine; Fenatrol; G 30027; Geigy 30,027; Gesaprim; Gesaprim 50; Gesaprin; Gesoprim; Griffex; Herbatoxol; Hungazin; Hungazin (VAN); Hungazin PK; Inakor; Oleogesaprim; Pitezin; Primatol; Primatol A; Primaze; Radazin; Radizin; Shell atrazine herbicide; Strazine; Triazine A 1294; Vectal; Vectal SC; Weedex A; Wonuk; Zeapos; Zeazin; Zeazine; Zeopos; s-Triazine, 2-chloro-4-ethylamino-6-isopropylamino-; [ChemIDplus]
Category
Herbicides, Triazine
Description
Colorless or white, odorless, crystalline powder. [herbicide]; [NIOSH]
Sources/Uses
The triazines are broadleaf herbicides. "Atrazine currently is one of the two most widely used agricultural pesticides in the U.S. (based on pounds of active ingredient applied per year). About two thirds of field corn and sorghum acres are treated with atrazine annually for weed control, accounting for most of the 64 to 80 million pounds used per year. Other uses are for turf and lawns, pineapples, sugarcane, wheat, and macadamia nuts." [EPA OPP web site] Used as a herbicide to control weeds in corn, asparagus, tomato, potato, and ornamental plantings; [ACGIH]
Comments
The following herbicides have an oral LD50 of >1 gm/kg and have little or no acute toxicity in humans: Alachlor, Amitrole, Ammonium sulfamate, Atrazine, Dalapon, Dicamba, Glyphosphate, Monuron, Oryzalin, Picloram, Propanil, Simazine, etc. [LaDou, p. 613] A mild skin irritant; Injury to the brain, heart, liver, lungs, kidneys, ovaries, and endocrine organs are observed in chronic feeding studies of experimental animals. [EXTOXNET] For the triazine herbicides, systemic toxicity unlikely unless large amounts are ingested; May cause irritation; [EPA Pesticides, p. 121] TLV basis: hematologic, reproductive and developmental effects; 3.3 mg/kg/day is NOEL in chronic feeding studies of rats for anemia and mammary tumors. [ACGIH] "Our analyses did not find any clear associations between atrazine exposure and any cancer analyzed." [PMID 15367570]
Reference Link #1
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
2 mg/m3, inhalable fraction
MAK
1 mg/m3, inhalable fraction
Vapor Pressure
3E-07 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Confirmed Animal

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: