tert-Butyl acetate
Agent Name
tert-Butyl acetate
CAS Number
540-88-5
Formula
C6-H12-O2
Major Category
Solvents
Synonyms
1,1-Dimethyl acetate; Acetic acid, 1,1-dimethylethyl ester; Acetic acid, tert-butyl ester; TLA; Texaco lead appreciator; t-Butyl acetate; tert-Butyl acetate; tert-Butyl ethanoate; [ChemIDplus] UN1123
Category
Esters (<C12)
Description
Colorless liquid with a fruity odor; [NIOSH]
Sources/Uses
Used as a solvent (industrial coatings, inks, adhesives, cleaners) and gasoline additive; Bananas and other fruits are food sources. [ACGIH]
Comments
Liver changes were seen in animals exposed to 7900 mg/m3. [ACGIH] A throat and eye irritant; [CAMEO] Inhalation of high concentrations can cause CNS depression; [CHEMINFO]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
50 ppm
STEL (ACGIH)
150 ppm
PEL (OSHA)
200 ppm
MAK
20 ppm
IDLH (NIOSH)
1500 ppm
Excerpts from Documentation for IDLHs
Exposures of 200 to 300 ppm cause slight irritation of the eyes and nose, and short exposures to 3,300 ppm cause extreme irritation of the eyes and nose [ILO 1983].
Vapor Pressure
47 mm Hg
Odor Threshold Low
4 ppm
Odor Threshold High
47 ppm
Explanatory Notes
IDLH = 10% LEL (lower explosive limit); Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards"; Flash point = 72 deg F; VP from HSDB;
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: