Captan

Synonyms

N-Trichloromethylthio-4-cyclohexane-1,2-dicarboximide; Vancide 89; Dangard; Merpan; Orthocide-406; SR-406; [Marks, p. 268] Agrox; Captal; Captec; Captol; Captonex; Clomitane; Merpan; Meteoro; Orthocide; Phytocape; Sepicap; Sorene; Vancide 89; [EXTOXNET]

Category

Fungicides

Description

Odorless, white, crystalline powder. [fungicide] [Note: Commercial product is a yellow powder with a pungent odor.]; [NIOSH]

Sources/Uses

The thiophthalimides are widely used fungicides on seeds, field crops, and stored produce; [EPA Pesticides] Captan is also used as a biocide in paints, polishes, shampoos, and cosmetics. [Kanerva, p. 1765] No longer used as a fungicide in hair-care products; [Kanerva, p. 1516]

Comments

The thiophthalimides include captan, captafol and folpet; no systemic poisonings in humans have been reported; [EPA Pesticides] Captan is an agricultural fungicide that has caused occupational allergic contact dermatitis usually after airborne exposure. [Marks, p. 267] Allergic contact dermatitis also reported in hairdressers, painters, polishers, and varnishers; [Kanerva, p. 1765] In high-dose reproductive animal studies, captan causes testicular damage and fetal losses. It is a possible teratogen. [Frazier, p. 232-4] Not teratogenic in rats; Teratogenic in hamsters at a single dose of >750 mg/kg on day 7 or 8 of gestation; [ACGIH]

Most uses on food crops were cancelled by the EPA in 1989 [EXTOXNET]

Reference Link #1

Biomedical References

No

5 mg/m3, inhalable particulate matter

Reference Link #2

Yes

Yes

Not classifiable

Confirmed Animal

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)