Azoxybenzene
Agent Name
Azoxybenzene
CAS Number
495-48-7
Formula
C12-H10-N2-O
Major Category
Nitrogen Compounds
Synonyms
Azobenzene, oxide; Azossibenzene [Italian]; Azoxybenzeen [Dutch]; Azoxybenzide; Azoxybenzol [German]; Azoxydibenzene; Benzene, azoxydi-; Diazene, diphenyl-, 1-oxide; Diphenyldiazene 1-oxide; Fenazox [German]; Fentoxan; Ordinary azoxybenzene; [ChemIDplus]
Category
Other Aromatics (Nitrogen)
Description
Yellow solid; mp = 36 deg C; [HSDB] Bright yellow or yellowish-brown solid; mp = 36 deg C; [CAMEO] Orange solid; mp = 33-36 deg C; [Alfa Aesar MSDS]
Sources/Uses
Used as an intermediate for dyes, an insecticide, and an agent for diagnosis and control of varroa jacobsoni and acarapis woodi on bees; [HSDB]
Comments
External application to rabbit eyes scored 1 on a scale of 1-10 (10 being most severe) for degree of injury after 24 hours; Causes icteric skin, methemoglobinemia, swelling of liver and spleen, and atrophy of testis and epididymis in oral studies of rats and mice; Emergency treatment: Methemoglobinemia; [HSDB] Dust mixtures with air may be explosive; A skin and eye irritant; May cause liver and kidney injury; [CAMEO] Causes decrease in cellular immune response in intraperitoneal toxic-dose studies of rats; Causes other GI and liver changes in oral lethal-dose studies of mice; [RTECS] May cause irritation and methemoglobinemia; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: