Demeton
Agent Name
Demeton
Alternative Name
Systox
CAS Number
8065-48-3
Formula
C8-H19-O3-P-S2.C8-H19-O3-P-S2
Major Category
Pesticides
Synonyms
BAY 10756; Bayer 8169; Demox; Diethoxythiophosphoric acid ester of 2-ethylmercaptoethanol; E 1059; ENT 17,295; Ethyl systox; Mercaptofos; Mercaptophos; O,O-Diethyl 2-ethylmercaptoethyl thiophosphate; O,O-Diethyl O(and S)-2-(ethylthio)ethyl phosphorothioate mixture; Septox; Systemox; Systox; beta-Ethylmercaptoethyl diethyl thionophosphate; Phosphorothioic acid, O,O-diethyl O-(2-(ethylthio)ethyl) ester, mixt. With O,O-diethyl S-(2-(ethylthio)ethyl) phosphorothioate; [ChemIDplus] UN3018
Category
Organophosphate Insecticides
Description
Amber, oily liquid with a sulfur-like odor. [insecticide]; [NIOSH] Colorless liquid; [ICSC]
Sources/Uses
Used as an insecticide, especially on ornamentals and nursery stock; [HSDB]
Comments
Its toxicity and potency are similar to that of parathion. [ACGIH] A cholinesterase inhibitor that may cause cardiac disorders, convulsions, cyanosis, and respiratory failure; Can be absorbed through skin; [ICSC] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Restricted
Cancelled--no longer registered as a pesticide for use in the US; [HSDB]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.05 mg/m3, inhalable fraction and vapor
PEL (OSHA)
0.1 mg/m3
IDLH (NIOSH)
10 mg/m3
Vapor Pressure
0.0003 mm Hg
Lethal Concentration
LCLo (cat) = 15 mg/m3/4hr
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."
Adverse Effects
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: