Blasticidin-S

Synonyms

Bla-S; Blastizidin [German]; TOA bla-S; 1-(1'-Cytosinyl)-4-(L-3'-amino-5'-(1''-N-methylguanidino)valerylamino)-1,2,3,4-tetradeoxy-beta-D-erythro-hex-2-enuronic acid; D-erythro-Hex-2-enopyranuronic acid, 4-(3-amino-5-(1-methylguanidino)valeramido)-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-; beta-D-erythro-Hex-2-enopyranuronic acid, 4-((3-amino-5-((aminoiminomethyl)methylamino)-1-oxopentyl)amino)-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-, (S)-; [ChemIDplus] UN3172

Category

Fungicides

Description

Colorless solid; Soluble in water; Technical product is light brown solid; [HSDB]

Sources/Uses

A nucleoside antibiotic produced by Streptomyces griseochromogenes; Used as a fungicide for rice blast disease in Japan; [Merck Index]

Comments

A mucous membrane irritant; A severe eye irritant; In cases of suicide after ingestion, patients had vomiting, diarrhea, sore throat, and abdominal pain; Findings in more severe cases included hypotension, arrhythmias, cyanosis, aspiration pneumonitis, and coma. [HSDB]

Biomedical References

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxins, extracted from living sources, solid, n.o.s."

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)