Diisopropanolamine
Agent Name
Diisopropanolamine
CAS Number
110-97-4
Formula
C6-H15-N-O2
Major Category
Nitrogen Compounds
Synonyms
1,1'-Iminobis-2-propanol; 1,1'-Iminodi-2-propanol; Bis(2-hydroxypropyl)amine; Bis(2-propanol)amine; DIPA; DIPA (alcohol); Di-2-propanolamine; Diisopropanolamine; Dipropyl-2,2'-dihydroxy-amine; N,N-Bis(2-hydroxypropyl)amine; 1,1'-Iminodipropan-2-ol; 2-Propanol, 1,1'-iminobis-; 2-Propanol, 1,1'-iminodi-; [ChemIDplus] UN3259
Category
Amines, Aliphatic
Description
White hygroscopic solid; Yellows upon light and air exposure; mp = 42 deg C; [ICSC] May also be in the form of colorless liquid; Odor of dead fish; [CAMEO] White solid; mp = 43-47 deg C; [MSDSonline]
Sources/Uses
Used as chemical intermediate, emulsifying agent (polishes, textile specialties, leather compounds, insecticides, cold wave permanent hair solutions, and water paints), antimicrobial agent in cutting fluids, and for removal of hydrogen sulfide and carbon dioxide from natural and industrial gases; Also used in adhesives, paper and paperboard, coatings, food packaging, and in prescription drugs; [HSDB]
Comments
A skin, eye, and nasal irritant; No allergic or photoallergic dermatitis observed in 25 volunteers; Weak skin sensitization reported from occupational exposure; Causes burns to rabbit eyes; Causes severe necrosis to rabbit skin; [HSDB] An eye irritant; [eChemPortal: ESIS] Hypothermia, diarrhea, uncoordinated movements, and seizures observed in lethal-dose animal studies; [IUCLID] No effects on fetal development when administered by gavage to pregnant rats; No data on effects to human pregnancy; [REPROTOX] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Can be absorbed through skin; Inhalation may cause pulmonary edema; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
0.000125 mm Hg
Lethal Concentration
LC50 (rat) > 795 mg/m3
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Amines, solid, corrosive, n.o.s."
NFPA
must be preheated
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Processes