Fluthiacet-methyl

Synonyms

Action; CGA 248757; KIH 9201; Acetic acid, ((2-chloro-4-fluoro-5-((tetrahydro-3-oxo-1H,3H-(1,3,4)thiadiazolo(3,4-a)pyridazin-1-ylidene)amino)phenyl)thio)-, methyl ester; [ChemIDplus]

Category

Herbicides, Protox-Inhibiting

Description

White solid; [Merck Index]

Sources/Uses

Used as selective post-emergence herbicide for control of broadleaf weeds in field corn and soy beans; Also used as cotton defoliant; [HSDB]

Comments

Introduced in 1964, Nitrofen was the first Protox-inhibiting herbicide. The first generation were diphenyl ethers. Newer Protox inhibitors usually consist of heterobicyclic molecules with one phenyl ring attached to a heterocyclic ring. Most are post-emergence herbicides. They are not known to be a threat to the environment. Concerning their effects on porphyrin metabolism, Protox-inhibiting herbicides are not considered to be a significant risk in healthy individuals. Variegate porphyria-like symptoms are observed in animals fed high doses, but porphyrin levels return to normal within a few days after ending the experiment. [Krieger, p. 1733-47]

Reference Link #1

Biomedical References

3.31E-09 mm Hg

LC50 (rat) >5,000 mg/m3

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)