Glyphosate

Synonyms

Gallup; Landmaster; Pondmaster; Ranger; Roundup; Rodeo; Touchdown; [EXTOXNET] CP 67573; Glyphosate; Glyphosphate; MON 2139; MON 6000; N-(Phosphonomethyl)glycine; Phosphonomethyliminoacetic acid; Roundup Max; Silglif; Glycine, N-(phosphonomethyl)-; [ChemIDplus]

Category

Herbicides, Other

Description

White solid; [Merck Index] Colorless solid; [ICSC]

Sources/Uses

A systemic herbicide commonly used for roadside and forest applications; [EXTOXNET]

Comments

TLV Basis includes liver damage and cataract. [ACGIH TLVs and BEIs] An irritant to the eyes, skin, and upper respiratory tract; [EPA Pesticides] The following herbicides have an oral LD50 of >1 gm/kg and have little or no acute toxicity in humans: Alachlor, Amitrole, Ammonium sulfamate, Atrazine, Dalapon, Dicamba, Glyphosphate, Monuron, Oryzalin, Picloram, Propanil, Simazine, etc. [LaDou, p. 613] A severe eye and mild skin irritant; [ICSC] It was found not to be a skin sensitizer after extensive investigation. [Kanerva, p. 782] “In the AHS [Agricultural Health Study], there was no association between glyphosate exposure and NHL [non-Hodgkin lymphoma] . . . there is little evidence of biologic effects of glyphosate in humans; therefore, no clear biologic mechanism has been proposed.” [Occupational Cancers, p. 505] ""There was no pattern of increasing risk of NHL overall with increasing years of use of glyphosate." [PMID 31246262] See "Glyphosate isopropylamine salt."

Reference Link #1

Biomedical References

5 mg/m3, inhalable particulate matter

9.8E-08 mm Hg

Explanatory Notes

VP from HSDB;

Reference Link #2

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Probable (2a)

Not Classifiable

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)