Tri(2-butoxyethyl) phosphate

Synonyms

2-Butoxyethanol, phosphate; Ethanol, 2-butoxy-, phosphate (3:1); KP 140; Kronitex KP-140; Phosflex T-BEP; Phosphoric acid, tributoxyethyl ester; Phosphoric acid, tris(2-butoxyethyl) ester; TBEP; Tri(2-butoxyethanol) phosphate; Tri(2-butoxyethanol)phosphate; Tributoxyethyl phosphate; Tributyl cellosolve phosphate; Tris(2-butoxyethyl) phosphate; Tris(butoxyethyl) phosphate; Tris-(2-butoxyethyl)fosfat [Czech]; [ChemIDplus]

Category

Organophosphates, Other

Description

Slightly yellow liquid with a sweetish odor; [HSDB]

Sources/Uses

Used as a plasticizer for resins and elastomers, in floor finishes and waxes, as a flame retardant, as a plasticizer for rubber stoppers in blood specimen containers, and as a fire-resistant and light-stable plasticizer for products intended for food contact; Occupational exposure is likely to be by skin absorption during production and from floor polishes; [HSDB] Used as solvent for resins, a viscosity modifier in plastisols, and an antifoam agent for synthetic rubber, plastics, and lacquers; [INCHEM]

Comments

Irritating to skin and eyes; The liver is the target organ in high-dose animal studies; Has anticholinesterase action at lethal doses; Skin absorption is expected to be low; No effect on neuropathy target esterase (NTE), but cholinesterases were inhibited in treated hens; [HSDB] An irritant; [MSDSonline]

Reference Link #1

Biomedical References

2.5E-08 mm Hg

LC (rat) > 600 mg/m3/6h

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Painting (Pigments, Binders, and Biocides)