N-Nitrosodi-n-propylamine
Agent Name
N-Nitrosodi-n-propylamine
Alternative Name
NDPA
CAS Number
621-64-7
Formula
C6-H14-N2-O
Major Category
Nitrogen Compounds
Synonyms
NDPA; 1-Propanamine, N-nitroso-N-propyl-; Di-n-propylnitrosamine; Di-n-propylnitrosoamine; Dipropylamine, N-nitroso-; Dipropylnitrosamine; N,N-Di-n-propylnitrosamine; N,N-Dipropylnitrosamine; N-Nitroso-N-propyl-1-propanamine; N-Nitrosodi-n-propylamine; N-Nitrosodipropylamine; Nitrosodipropylamine; Propanamine, N-nitroso-N-propyl-; Propylamine, N-nitroso-N-di-; [ChemIDplus] UN3077
Category
Nitrosamines
Description
Yellow liquid; [HSDB]
Sources/Uses
Not produced in the United States; used primarily for research; [HSDB] "Small amounts of N-nitrosodi-n-propylamine are produced as a side reaction during some manufacturing processes, as a contaminant in some commonly available weed killers (dinitroaniline-based), and during the manufacture of some rubber products. When exposed to sunlight, N-nitrosodi-n-propylamine usually does not last for more than a day." [ATSDR ToxProfiles]
Comments
In animal experiments, N-nitrosodi-n-propylamine causes hepatic injury after acute exposure and cancer of the liver after chronic exposure. [ATSDR ToxProfiles]
Biomedical References
Exposure Assessment
Vapor Pressure
0.39 mm Hg
Explanatory Notes
Carcinogen--No TLV; VP from HSDB;
Reference Link #2
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.